No chemotherapies have been FDA-approved for use in cats despite a growing need for such therapies. Paclitaxel (Taxol®) is one of the most effective anticancer agents used in human cancer therapy today, …
Hemangiosarcoma (HSA) is a highly aggressive and malignant vascular tumor occurring most commonly in dogs. Dogs with splenic hemangiosarcoma have a poor prognosis, with fewer than 20% of dogs surviving …
To address the limitations of traditional IACUC review of clinical research studies involving client-owned animals, the AVMA issued a policy describing the use of a veterinary clinical studies committee (VCSC), …
Osteosarcoma is an aggressive and highly metastatic cancer in both dogs and humans. Gefitinib, a small molecule receptor tyrosine kinase inhibitor that targets Epidermal Growth Factor Receptor (EGFR), approved as …
This is a multi-site prospective 6-9 patient escalation study with 3 canine patients per group, each group having progressively more difficult to access tumors that measure >5cm in diameter. The …
Ethical review of both human and animal research is critical to ensuring that studies are conducted with due regard to the welfare and safety of enrolled subjects and to the …
