|Accelerating medical discovery | Advancing veterinary care CASTR: Companion Animal Studies for Translational Research
CASTR Alliance aims to advance human and veterinary medicine by facilitating the discovery of innovative treatments through the management of high-quality veterinary clinical studies and collaboration with industry leaders and veterinary hospitals.
can expect all CASTR Alliance-run studies to be managed efficiently and ethically, adhere to GCP standards, and result in high quality data. We deliver progress updates upon request throughout the trial, conduct diligent site and safety monitoring, and provide data at interim analysis, and at the conclusion of the trial.
and support staff participating in the study are trained from the onset on the trial protocol to ensure treatment is conducted according to our rigorous standards. We continue to provide guidance and support to our participating sites throughout the entire course of the study.
who enroll their pets in these clinical studies engage directly with a participating veterinary center, where all study procedures are carried out in accordance with the established study protocol. Studies are typically supported such that treatment is partially or fully covered by the sponsor.
CASTR Alliance was founded in 2019 by veterinary clinician-scientists Jessica Bertout and Jim Perry. As scientists, they bring extensive experience in designing, managing, and conducting clinical trials that meet the rigorous standards of the biotech industry. Moreover, as devoted pet owners and veterinarians, they are personally committed to delivering the highest quality care for our animal companions. Together, Drs. Bertout and Perry created CASTR Alliance to leverage their expertise and advance medicine for humans and animals alike.
Hemangiosarcoma (HSA) is a highly aggressive and malignant vascular tumor occurring most commonly in dogs. Dogs with splenic hemangiosarcoma have a poor prognosis, with fewer than 20% of dogs surviving 9 months with …
To address the limitations of traditional IACUC review of clinical research studies involving client-owned animals, the AVMA issued a policy describing the use of a veterinary clinical studies committee (VCSC), analogous to an …
Osteosarcoma is an aggressive and highly metastatic cancer in both dogs and humans. Gefitinib, a small molecule receptor tyrosine kinase inhibitor that targets Epidermal Growth Factor Receptor (EGFR), approved as a first-line treatment …
This is a multi-site prospective 6-9 patient escalation study with 3 canine patients per group, each group having progressively more difficult to access tumors that measure >5cm in diameter. The first group will …
Ethical review of both human and animal research is critical to ensuring that studies are conducted with due regard to the welfare and safety of enrolled subjects and to the integrity of the …
Please reach out to us directly with any inquiries:
CASTR Alliance, Inc.
22525 SE 64th Place
Suite 2258
Issaquah, WA 98027
USA
