{"id":1576,"date":"2024-09-18T23:27:23","date_gmt":"2024-09-18T23:27:23","guid":{"rendered":"https:\/\/castr-wa.com\/?page_id=1576"},"modified":"2024-09-24T15:30:47","modified_gmt":"2024-09-24T15:30:47","slug":"translational-research","status":"publish","type":"page","link":"https:\/\/castr-wa.com\/?page_id=1576","title":{"rendered":""},"content":{"rendered":"\n<div class=\"wp-block-cover is-light\"><span aria-hidden=\"true\" class=\"wp-block-cover__background has-background-dim\"><\/span><img data-opt-id=593532105  fetchpriority=\"high\" width=\"2560\" height=\"1707\" src=\"https:\/\/mlis96lle3so.i.optimole.com\/cb:Xy5t.6338c\/w:auto\/h:auto\/q:mauto\/f:best\/ig:avif\/https:\/\/castr-wa.com\/wp-content\/uploads\/2024\/09\/pexels-samson-katt-5255240-scaled.jpg\" class=\"wp-block-cover__image-background wp-post-image\" alt=\"\" decoding=\"async\" data-object-fit=\"cover\" data-object-position=\"51% 32%\" style=\"object-position: 51% 32%\" loading=\"lazy\" srcset=\"https:\/\/mlis96lle3so.i.optimole.com\/cb:Xy5t.6338c\/w:1619\/h:1080\/q:mauto\/f:best\/ig:avif\/https:\/\/castr-wa.com\/wp-content\/uploads\/2024\/09\/pexels-samson-katt-5255240-scaled.jpg 2560w, https:\/\/mlis96lle3so.i.optimole.com\/cb:Xy5t.6338c\/w:300\/h:200\/q:mauto\/f:best\/ig:avif\/https:\/\/castr-wa.com\/wp-content\/uploads\/2024\/09\/pexels-samson-katt-5255240-scaled.jpg 300w, https:\/\/mlis96lle3so.i.optimole.com\/cb:Xy5t.6338c\/w:1024\/h:683\/q:mauto\/f:best\/ig:avif\/https:\/\/castr-wa.com\/wp-content\/uploads\/2024\/09\/pexels-samson-katt-5255240-scaled.jpg 1024w, https:\/\/mlis96lle3so.i.optimole.com\/cb:Xy5t.6338c\/w:768\/h:512\/q:mauto\/f:best\/ig:avif\/https:\/\/castr-wa.com\/wp-content\/uploads\/2024\/09\/pexels-samson-katt-5255240-scaled.jpg 768w, https:\/\/mlis96lle3so.i.optimole.com\/cb:Xy5t.6338c\/w:1536\/h:1024\/q:mauto\/f:best\/ig:avif\/https:\/\/castr-wa.com\/wp-content\/uploads\/2024\/09\/pexels-samson-katt-5255240-scaled.jpg 1536w, https:\/\/mlis96lle3so.i.optimole.com\/cb:Xy5t.6338c\/w:1620\/h:1080\/q:mauto\/f:best\/ig:avif\/https:\/\/castr-wa.com\/wp-content\/uploads\/2024\/09\/pexels-samson-katt-5255240-scaled.jpg 2048w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/><div class=\"wp-block-cover__inner-container\">\n<p class=\"has-text-align-center has-white-color has-text-color has-large-font-size\">TRANSLATIONAL RESEARCH<\/p>\n<\/div><\/div>\n\n\n\n<p><br>Studies with companion animals provide a vast array of benefits that differentiate them from human trials.<\/p>\n\n\n\n<ul>\n<li>Spontaneous diseases in companion animals recapitulate human diseases much more closely than do diseases induced in laboratory animals, often sharing similar etiologies, progressions, pathobiologies, and molecular changes.<\/li>\n\n\n\n<li>A higher incidence in dogs of some diseases (e.g. osteosarcoma, lymphoma, or soft tissue sarcoma) that are rare in humans allow studies to enroll and be completed faster.<\/li>\n\n\n\n<li>Breed predispositions to disease provide a means of identifying underlying mutations and treatable targets that may otherwise be difficult to study in humans.<\/li>\n\n\n\n<li>An intact immune system provides an ideal background for the study of immunotherapies, tumor microenvironment, and the microbiome.<\/li>\n\n\n\n<li>Unlike lab animals, companion animals live in the same environment as people and may, like people, have other concomitant diseases.<\/li>\n\n\n\n<li>Often, lack of standard of care treatments makes it possible to utilize novel therapies in veterinary patients much earlier in the disease process than most human trials.<\/li>\n\n\n\n<li>A shorter natural lifespan means our dogs and cats progress faster through stages of disease, accelerating study timelines.<\/li>\n\n\n\n<li>Importantly, positive outcomes in veterinary studies may encourage parallel development of the product for the animal health market, or future off-label use of the product by veterinarians, thus providing novel solutions for veterinary patients in need.<\/li>\n<\/ul>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"has-text-align-center has-medium-font-size\" style=\"font-style:normal;font-weight:600\"><a href=\"https:\/\/castr-wa.com\/#whattoexpect\">BACK<\/a><\/h2>\n","protected":false},"excerpt":{"rendered":"<p>Studies with companion animals provide a vast array of benefits that differentiate them from human trials. BACK<\/p>\n","protected":false},"author":1,"featured_media":1834,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"_links":{"self":[{"href":"https:\/\/castr-wa.com\/index.php?rest_route=\/wp\/v2\/pages\/1576"}],"collection":[{"href":"https:\/\/castr-wa.com\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/castr-wa.com\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/castr-wa.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/castr-wa.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1576"}],"version-history":[{"count":13,"href":"https:\/\/castr-wa.com\/index.php?rest_route=\/wp\/v2\/pages\/1576\/revisions"}],"predecessor-version":[{"id":1914,"href":"https:\/\/castr-wa.com\/index.php?rest_route=\/wp\/v2\/pages\/1576\/revisions\/1914"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/castr-wa.com\/index.php?rest_route=\/wp\/v2\/media\/1834"}],"wp:attachment":[{"href":"https:\/\/castr-wa.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1576"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}